Liver & Biliary Tumours

Primary and metastatic tumours of the liver and bile duct system.

What is Liver & Biliary Tumours?

Primary liver tumours are less common than metastatic disease. The most common primary form is hepatocellular carcinoma, which frequently presents as a single large ('massive') lobe tumour that can be surgically removed with a good prognosis. Nodular and diffuse forms carry a worse outlook.

Common signs and symptoms

Signs vary between dogs and can be subtle at first. Watch for the following, especially if several appear together or persist for more than a few days:

  • Vague reduced appetite and weight loss
  • Abdominal distension
  • Vomiting or diarrhoea
  • Jaundice (with biliary tumours)
  • Sudden collapse if a tumour ruptures and bleeds

Risk factors

Certain dogs are more predisposed. Understanding risk helps you screen earlier and act sooner.

  • Senior dogs (typically 10+)
  • Chronic liver disease or cirrhosis (rare risk factor in dogs)

When to see a vet

Use this as general triage guidance, not a substitute for veterinary advice.

  • Book a routine appointment if: unexplained weight loss, elevated liver enzymes on routine bloodwork, or a palpable abdominal mass.
  • Seek urgent care if: pale gums, sudden weakness, or collapse — a bleeding liver mass is a surgical emergency.

Diagnosis and management

Diagnosis uses bloodwork, abdominal ultrasound or CT, and biopsy. Surgical lobectomy of a single massive tumour can be curative for hepatocellular carcinoma. Chemotherapy is reserved for specific tumour types.

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